منابع مشابه
Plasma enzyme activities in primary hypothyroidism.
Results of clinical chemistry tests are often initially interpreted by relatively inexperienced junior medical staff, and therefore a major role of clinical chemists is to ensure that their laboratory tests are utilized and interpreted appropriately. The cases described below demonstrate the interaction of a diagnostic problem and clinical inexperience in an area where clinical chemists can, an...
متن کاملHypothyroidism due to enzyme defects.
Defects in thyroid hormone production, transport and utilization are classified. Particular attention is given to inherited intrathyroidal defects in hormone synthesis which impair thyroid function and lead to goitre formation and hypothyroidism. Anomalies in biosynthesis may also result from disease or drugs. Reference is made to the derangement of iodine metabolism that results from iodine de...
متن کاملEffects of experimentally-induced maternal hypothyroidism on crucial offspring rat brain enzyme activities.
Hypothyroidism is known to exert significant structural and functional changes to the developing central nervous system, and can lead to the establishment of serious mental retardation and neurological problems. The aim of the present study was to shed more light on the effects of gestational and/or lactational maternal exposure to propylthiouracil-induced experimental hypothyroidism on crucial...
متن کاملRegulation of Enzyme Activities
spora crassa has been studied. Elevation of ATCase (L-aspartate carbamoyltransferase) activity is found in all pyrimidine-requiring mutants when they are starved for uridine. DHOase (dihydroorotase) is an unstable enzyme, and it is impossible to conclude what type of regulation, if any, controls this enzyme. DHOdehase (dihydroorotate dehydrogenase) activity shows a marked elevation in uridine-s...
متن کاملCongenital hypothyroidism alters the oxidative status, enzyme activities and morphological parameters in the hippocampus of developing rats
Congenital hypothyroidism is associated with delay in cell migration and proliferation in brain tissue, impairment of synapse formation, misregulation of neurotransmitters, hypomyelination and mental retardation. However, the mechanisms underlying the neuropsychological deficits observed in congenital hypothyroidism are not completely understood. In the present study we proposed a mechanism by ...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1984
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/30.11.1890a